- Author
-
V. Guglielmi
- Title
- Mind the heart
- Subtitle
- Embolic sources of stroke along the heart-brain axis
- Supervisors
-
Y.B.W.E.M. Roos
C.B.L.M. Majoie - Co-supervisors
-
J. Coutinho
R.N. Planken - Award date
- 22 January 2021
- Number of pages
- 220
- ISBN
- 9789492303387
- Document type
- PhD thesis
- Faculty
- Faculty of Medicine (AMC-UvA)
- Abstract
-
The aim of this thesis is to improve detection of embolic sources of ischemic stroke along the heart-brain axis. The structure of the thesis follows this anatomical pathway.
In the first part of this thesis (The Heart), we focused on sources of embolism from the heart which are detected through imaging. We performed three studies on the diagnostic yield of cardiac CT-angiography for detection of high-risk cardio-aortic sources of embolism in acute ischemic stroke patients. In the second part of this thesis (The Arteries), we explored (rare) sources of embolism from the arteries in an effort to increase awareness in the medical community. We conducted studies in ischemic stroke patients with an underlying acute aortic dissection, multiple cervical artery dissections, and a carotid web. In addition, we investigated the hypothesis that patients with ischemic stroke due to cervical carotid atherosclerosis have a more extensive collateral circulation and better outcomes than patients with cardioembolism. - Persistent Identifier
- https://hdl.handle.net/11245.1/a6c45326-0738-46d5-923c-929768acf102
- Downloads
-
Thesis (complete)
Front matter
Chapter 1: General introduction and thesis outline
Chapter 2: CT-angiography versus echocardiography for detection of cardiac thrombi in ischemic stroke: A systematic review and meta-analysis
Chapter 3: Non-gated cardiac CT-angiography for detection of cardio-aortic sources of embolism in the acute phase of ischemic stroke
Chapter 4: Mind the heart: ECG-gated cardiac CT-angiography in the acute phase of ischemic stroke – Rationale and study design
Chapter 5: Aortic dissection masquerading as a "code stroke": A single-center cohort study
Chapter 6: Triple and quadruple cervical artery dissections: A systematic review of individual patient data
Chapter 7: Collateral circulation and outcome in atherosclerotic versus cardioembolic large vessel occlusion
Chapter 8: Letter to the editor: Classic radiological appearance of a carotid web
Chapter 9: Recurrent stroke risk in patients with a carotid web
Chapter 10: General discussion
Summary; Dutch summary (Nederlandse samenvatting); Abbreviations; Contributing authors and affiliations; Publications; PhD portfolio; Acknowledgements (Dankwoord); About the author
- Supplementary materials
Disclaimer/Complaints regulations
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.