- Author
-
X. Zhang
- Title
- Probe pressure effects on Multi-Diameter Single Fiber Reflectance spectroscopy measurements
- Supervisors
- Co-supervisors
-
D.J. Faber
- Award date
- 6 May 2020
- Number of pages
- 146
- Document type
- PhD thesis
- Faculty
- Faculty of Medicine (AMC-UvA)
- Abstract
-
Multi-Diameter Single Fiber Reflectance spectroscopy (MDSFR) allows rapid and noninvasive extraction of tissue optical properties which requires the fiberoptic fiber to be placed in contact with the tissue. To ensure a good optical contact, the application of probe pressure is inevitable and usually not well controlled. This thesis focuses on investigating the effects of probe pressure on Multi-Diameter Single Fiber Reflectance spectroscopy measurements and studying the underlying mechanisms of the pressure-induced optical property changes. Furthermore, our research involves further improvement of both the measurement approach and the data-analyzing model, leading to exploitation of new functionality.
- Persistent Identifier
- https://hdl.handle.net/11245.1/7917c784-2049-4c4d-8957-af3a78c45f3f
- Downloads
-
Thesis (complete)
Front matter
1: Introduction
2: Single Fiber Reflectance spectroscopy calibration
3: Refractive index measurement using Single Fiber Reflectance spectroscopy
4: Multi-Diameter Single Fiber Reflectance spectroscopy of heavily pigmented skin: Modeling the inhomogeneous distribution of melanin
5: Effect of probe pressure on skin tissue optical properties measurement using Multi-Diameter Single Fiber Reflectance spectroscopy
6: Discussion and outlook
Summary; Samenvatting; Portfolio; Acknowledgement
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